By Luan D. Truong, Steven S. Shen, Jae Y. Ro, Philip T. Cagle
Frozen sections are played whereas a sufferer is present process surgical procedure as a foundation for making a right away analysis that may impression therapy judgements. Frozen part prognosis is usually a hugely challenging state of affairs for the pathologist who needs to render a prognosis quick for the sufferer and surgeon.
The Frozen part Library series will offer concise, effortless, website particular handbooks which are good illustrated and spotlight the pitfalls, artifacts and differential analysis concerns that come up within the moved quickly frozen part scenario.
Luan D. Truong, M.D., is Professor of Pathology and Laboratory medication, The Methodist clinic and Weill clinical collage of Cornell college and Adjunct Professor of Pathology & medication, Baylor collage of Medicine.
Jae Y. Ro, M.D., Ph.D., is Professor of Pathology and Laboratory drugs, The Methodist health center and Weill clinical collage of Cornell University.
Steven S. Shen, M.D., Ph.D., is affiliate Professor of Pathology and Laboratory medication, The Methodist health facility and Weill scientific university of Cornell University.
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A) Most areas of the cystic tumor shown in Fig. 29d show necrotic material and macrophages lining a fibrous wall. These changes, however, strongly suggest the diagnosis of cystic papillary RCC. (b) Additional samplings for FS show an area of papillary carcinoma in the wall. 17,18 Specimen Handling Since partial nephrectomy is preferred for small peripheral and polar tumors, the resected specimen often includes renal tissue and perirenal adipose tissue. Central tumors, defined as those BookID 151197_ChapID 1_Proof# 1 - 19/08/2009 40 frozen section library: genitourinary tract with extension to the collecting system or renal sinus by imaging,36 are increasingly considered for partial nephrectomy.
19 The surgeon tends to be aware of the possibility of AML since, even in the above context, AML tends to respect the boundary of Gerota fascia, allowing the surgeon to excise the tumor along the natural tissue plane delineated by this fascia. This is not the case for bulky retroperitoneal liposarcoma. A correct FS diagnosis is also aided by an awareness of this type of AML, the presence of a constant, albeit small, intrarenal component, and microscopic fields of vascular/smooth muscle even in areas which grossly look like adipose tissue (Fig.
40 Pheochromocytoma. A large tumor involving both adrenal gland and kidney. Nests of tumor cells with abundant clear or faintly granular cytoplasm separated by dilated thin-walled blood vessels can simulate clear cell RCC. 41 Pheochromocytoma. (a) Another area simulating clear cell RCC. (b) The touch prep, however, shows typical cytological features of pheochromocytoma, that is, small clusters and isolated cells or bare nuclei, with round nuclear contour and clumpy chromatin. 42 Primary renal lymphoma.